Platelet-Rich Plasma (PRP)

What Are PRP, PRF and EZ Gel?

Platelet-Rich Plasma (PRP), Platelet-Rich Fibrin (PRF) and EZGel all involve using a person’s own blood to create a concentrate of one’s own platelets, which then is injected into a specific area of the body to promote healing and tissue regeneration. Platelets are a type of blood cell that play a crucial role in clotting and wound healing due to the growth factors that they contain which enhance microcirculation and stimulate production of new collagen.

While PRF is similar to PRP, they are not the same. Some preparations of PRF contain a higher concentration of platelets and white blood cells, and form a gel-like consistency due to the presence of fibrin, which helps with application and retention at the treatment site.

EZGel is yet again different from PRP and PRF due to the addition of denatured albumin also from the patient’s own blood, which creates an even thicker and stiffer product. This allows the growth factors to be released in a “slow drip” fashion over the course of days to weeks, and also give an immediate appearance of more volume, much like a filler.

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The Procedure

All of these regenerative procedures start with obtaining blood through a blood draw, which is then run through a spinning process called centrifugation to isolate the desired components of the blood.

PRP and PRF can both be injected or microneedled into the skin where facial and skin rejuvenation is desired. They can also be microneedled and injected into the scalp to stimulate hair follicle growth. They can also be applied after laser procedures to augment results and speed up healing. EZGel can be particularly effective when injected into areas where not only skin rejuvenation is desired, but where volume has been lost, such as in undereye hollows as it not only helps with rejuvenation but gives an immediately improved appearance.

The End Result

With PRP and PRF, results won’t be immediately noticeable. It usually takes a couple of weeks to begin to see the effects and multiple treatments over time can help build results even further.

PRP, PRF and EZGel given by injection, microneedling, or used in conjunction with lasers can help to:

  • Blend away acne scars 
  • Reduce the appearance of sun damage 
  • Diminish fine lines and wrinkles 
  • Reduce pore size and improve skin tone 
  • Increase skin firmness and elasticity 
  • Help restore volume, such as in the undereyes 


There may be some redness, mild swelling and occasionally some bruising all of which are all likely to resolve within a few days. Taking oral arnica preparations that you can find from your local health food store can help with speeding up recovery process. 

It really depends on the severity of the issue that is being addressed, but it may take 3 or more treatments to achieve best results (for example acne scarring or undereye hollows). 

It depends on the extent of the desired treatment, but usually takes about 45 minutes, longer in some cases. 

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